Gel with 78 mg/g 5-aminolevulinic acid hydrochloride

Cream for plaque psoriasis containing calcipotriol 50 mcg/g and betamethasone 0.5 mg/g equivalent.

An oral treatment for plaque psoriasis containing dimethyl fumarate.

A cream containing urea 5% and ceramide.

A cutaneous solution for acne, with each gram of solution containing 40 mg of erythromycin and 0.25 mg of tretinoin.

A cutaneous solution containing 5 mg of fluorouracil and 100 mg of salicylic acid per 1g of solution.

Rinvoq (upadacitinib) is a selective and reversible Janus kinase (JAK) inhibitor. JAKs are intracellular enzymes that transmit cytokine or growth factor signals involved in a broad range of cellular processes including inflammatory responses, hematopoiesis, and immune surveillance. The JAK family of enzymes contains four members, JAK1, JAK2, JAK3 and TYK2 which work in pairs to phosphorylate and activate signal transducers and activators of transcription (STATs). This phosphorylation, in turn, modulates gene expression and cellular function. JAK1 is important in inflammatory cytokine signals while JAK2 is important for red blood cell maturation and JAK3 signals play a role in immune surveillance and lymphocyte function.

Nemolizumab is a humanized monoclonal antibody of the IgG2 subclass that inhibits IL-31 signaling by binding selectively to IL-31RA. IL-31 is a neuroimmune cytokine that drives pruritus and inflammation, which are important pathophysiological components of atopic dermatitis and prurigo nodularis. IL-31 has an additional barrier dysfunction effect in atopic dermatitis, and epidermal differentiation and profibrotic effect in prurigo nodularis.

Range of silicone-based medical adhesive removers and barrier wipes that are designed to be used in conjunction with a medical adhesive product, such as a sheath or stoma pouch.

Soothing, protecting and hydrating emollient cream containing urea 5% and glycerine 5%. Apply plenty of product to achieve results.