Dermatology Handbook
For UK audiences

The essential guide to product selection

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Cutivate
GSK

Cutivate

Cutivate contains fluticasone propionate which is a potent topical corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties
Betnovate
GSK

Betnovate

Betamethasone valerate is potent corticosteroid with topical anti-inflammatory activity and pruritic manifestations of steroid responsive dermatoses
Eumovate
GSK

Eumovate

Clobetasone butyrate is a moderately potent topical corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of steroid responsive dermatoses
Betnovate-RD
GSK

Betnovate-RD

Betamethasone is a corticosteroid with topical anti-inflammatory activity. Betamethasone valerate ready diluted (Betnovate RD) preparations are indicated for maintenance treatment once an acute episode has been treated effectively with a continuous course of betamethasone valerate (Betnovate).
Driclor
GSK

Driclor

Driclor acts locally, in the stratum corneum and the terminal duct to relieve hyperhidrosis. Aluminium chloride hexahydrate is acidic and is thought to act by diffusing into the sweat ducts where on neutralisation it forms gelatinous hydroxides which obstruct the flow of sweat. The antiperspirant effect of aluminium chloride hexahydrate is partly explained by production of mechanical blockage in the eccrine sweat duct. Following application, aluminium is found in the stratum corneum and intra-luminally in the terminal duct
Lamisil Once Cutaneous Solution
GSK

Lamisil Once Cutaneous Solution

Lamisil contains terbinafine, an allylamine which has a broad spectrum of antifungal activity. At low concentrations terbinafine is fungicidal against dermatophytes, moulds and certain dimorphic fungi. Its activity against yeasts is fungicidal or fungistatic, depending on the species. Terbinafine interferes specifically with fungal sterol biosynthesis at an early step. This leads to a deficiency in ergosterol and an intracellular accumulation of squalene, resulting in fungal cell death
Lamisil AT Spray
GSK

Lamisil AT Spray

Lamisil contains terbinafine, an allylamine which has a broad spectrum of antifungal activity. At low concentrations terbinafine is fungicidal against dermatophytes, moulds and certain dimorphic fungi. Its activity against yeasts is fungicidal or fungistatic, depending on the species. Terbinafine interferes specifically with fungal sterol biosynthesis at an early step. This leads to a deficiency in ergosterol and an intracellular accumulation of squalene, resulting in fungal cell death
Lamisil AT Gel
GSK

Lamisil AT Gel

Lamisil contains terbinafine, an allylamine which has a broad spectrum of antifungal activity. At low concentrations terbinafine is fungicidal against dermatophytes, moulds and certain dimorphic fungi. Its activity against yeasts is fungicidal or fungistatic, depending on the species. Terbinafine interferes specifically with fungal sterol biosynthesis at an early step. This leads to a deficiency in ergosterol and an intracellular accumulation of squalene, resulting in fungal cell death.
Alitretinoin (Toctino)
GSK

Alitretinoin (Toctino)

Contains a retinoid alitretinoin. The pharmacological action of retinoids may be explained by their effects on cell proliferation, cell differentiation, apoptosis, angiogenesis, keratinisation, sebum secretion and immunomodulation. Unlike other retinoids, which are specific agonists of either RAR or RXR receptors, alitretinoin binds to members of both receptor families. The mechanism of action of alitretinoin in chronic hand eczema is unknown. Alitretinoin has demonstrated immunomodulatory and anti-inflammatory effects that are relevant to skin inflammation
Bactroban
GSK

Bactroban

Bactroban contains mupirocin, an antibiotic. It has bacteriostatic properties at minimum inhibitory concentrations and bactericidal properties at the higher concentrations reached when applied locally