Aklief cream contains 50 micrograms (mcg/g) (w/w) trifarotene, which is a chemically stable, terphenyl acid derivative with retinoid-like activity. It is a potent RARγ agonist (retinoid acid receptor γ agonist), characterized by its high specificity to this receptor over RARα & RARβ (50- and 8-fold, respectively, with no Retinoid X Receptor (RXR) activity). In addition, trifarotene modulates retinoid target genes (differentiation and inflammatory processes) in immortalized keratinocytes and reconstructed epidermis.
Cutaneous treatment of acne vulgaris of the face and/or the trunk in patients from 12 years of age and older, when many comedones, papules and pustules are present.
Contains 2% salicylic acid, glycolic acid and gluconolactone acid.
A moisturising, non-greasy cream that alleviates the side effects often associtaed with acne medication and improves compliance. Ceramides support the skin’s protective barrier and reduce moisture loss. SymSitive helps to calm irritations, such as stinging and burning directly at source, and Licochalcone A helps to soothe irritations. The formula helps to bring demanding, blemish- and acne-prone skin under control.
Reduction and prevention of blemishes and post-acne marks. 95% agree: Finally beats post-acne marks. Triple Effect Serum with patented Thiamidol formulated to reduce post-acne marks, reduce blemishes (Salicylic Acid), and control shine. First visible results in 2 weeks. Protective Fluid with SPF 30 formulated to prevent blemishes, control shine, and protect post-acne marks from darkening due to the sun. Enhanced efficacy together with Triple Effect Serum.
Gel combination therapy of clindamycin and tretinoin. Clindamycin is a semisynthetic derivative of the parent compound lincomycin that is produced by Streptomyces lincolnensis and is predominantly bacteriostatic. Topical tretinoin has both comedolytic and anti-inflammatory effects. Tretinoin decreases cohesiveness of follicular epithelial cells resulting in decreased microcomedone formation. Additionally, tretinoin stimulates mitotic activity and increased turnover of follicular epithelial cells, causing extrusion of the comedones.